Hemophilia A: Moving Beyond Bleeds

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Young adult male looking at his infusion calendar

Feb 19, 2026

Types of Infusions for Treatment of Hemophilia

Hemophilia is an inherited bleeding disorder caused by a deficiency of either clotting factor VIII (hemophilia A) or IX (hemophilia B), leading to impaired blood clotting and an increased risk of prolonged or spontaneous bleeding. Clotting factor therapy, which involves intravenous administration of factor VIII or IX, restores the clotting and remains a cornerstone of hemophilia management.^1,2 While other treatments are available, this article focuses specifically on clotting factor replacement delivered through intravenous infusion.

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Dec 5, 2025

Factor VIII Activity Assays - A Guide to PK Testing

Pharmacokinetic (PK) testing with accurate Factor VIII assays may help personalize hemophilia A treatment.^1,2 This article reviews one-stage and chromogenic methods and their clinical use.

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Jan 3, 2025

The Risk of Factor VIII Inhibitors in Hemophilia A Treatment

Factor VIII (FVIII) replacement therapies have been a step forward for the prevention and treatment of bleeding episodes in patients with hemophilia A. One remaining challenge is the development of neutralizing antibodies, known as inhibitors, which interfere with patient response to a factor infusion or render it ineffective.

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Jan 3, 2025

Hemophilia A in Women - Key Points to Discuss With Your Patients

Hemophilia A–a rare bleeding disorder–often goes undiagnosed in women because of the misconception that it only affects men, due to its X-linked recessive inheritance pattern. Although factor levels above 50% are usually considered within the normal range, emerging data suggest that some women and girls with levels between 50% and 60% may still have an increased risk of bleeding symptoms. Additionally, they may have sex-specific symptoms such as heavy menstrual bleeding and postpartum hemorrhage. This highlights the need for a more nuanced understanding of hemophilia A as it pertains to women.

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Sep 10, 2024

Discussing Treatment Goals and Factor VIII Activity Assays With Hemophilia A Patients

Why is it important to accurately measure factor VIII activity levels when treating patients with hemophilia A? Because the results can help you tailor treatment plans and help inform personalized treatment goals. To aid in shared decision-making, it’s essential for patients to understand the significance of factor VIII activity level assay measurements. This knowledge can empower them to actively participate in their treatment plan, make informed decisions, and improve their day-to-day lives and overall well-being.

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Sep 9, 2024

Exploring Factor VIII Replacement Therapies: A Guide to Choosing the Right Treatment for Patients With Hemophilia A

Ensuring optimal care for patients with hemophilia A requires a thorough understanding of available treatment options, prioritization of bleed prevention and long-term joint health, and comprehensive patient education. This article will cover different types of factor VIII replacement therapies^* and will compare an on-demand versus prophylactic treatment approach with the goal of helping tailor treatment plans effectively, which can help enhance quality of life.

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