- Article
- Source: Campus Sanofi
- May 20, 2025
There is significant unmet need in the management of PN¹
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The clinical objective in PN is to relieve intense itch and heal nodular lesions, which may improve patients’ QoL2-4
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A multimodal treatment approach is recommended for PN by a US consensus panel2,
Treatment is selected based on a patient’s clinical presentation, comorbidities, and response to prior treatments and should address both neural and immunologic components of disease, which often requires use of multiple therapeutic agents2,5
- Mainly topical therapies
- Widespread skin-directed or systemic therapies
- Experimental therapies
There remains an unmet need in the management of PN1
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Qureshi AA, Abate LE, Yosipovitch G, Friedman AJ. A systematic review of evidence-based treatments for prurigo nodularis. J Am Acad Dermatol. 2019;80(3):756-764.
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Elmariah S, Kim B, Berger T, et al. Practical approaches for diagnosis and management of prurigo nodularis: United States expert panel consensus. J Am Acad Dermatol. 2021;84(3):747-760.
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Kowalski EH, Kneiber D, Valdebran M, Patel U, Amber KT. Treatment-resistant prurigo nodularis: challenges and solutions. Clin Cosmet Investig Dermatol. 2019;12:163-172.
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Ständer HF, Elmariah S, Zeidler C, Spellman M, Ständer S. Diagnostic and treatment algorithm for chronic nodular prurigo. J Am Acad Dermatol. 2020;82(2):460-468.
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Williams KA, Huang AH, Belzberg M, Kwatra SG. Prurigo nodularis: pathogenesis and management. J Am Acad Dermatol. 2020;83(6):1567-1575.
MAT-BH-2200541/V1/June 2022