<table border="1" cellpadding="10" cellspacing="1">
 <tbody>
 <tr>
 <td colspan="3" style="background-color: rgb(244, 242, 246);">Additional&nbsp;Signals</td>
 </tr>
 <tr>
 <td style="background-color: rgb(244, 242, 246);">Physiological&nbsp;Signals</td>
 <td style="background-color: rgb(244, 242, 246);">Advantages</td>
 <td style="background-color: rgb(244, 242, 246);">Limitations</td>
 </tr>
 <tr>
 <td>Continuous ketone and lactate sensors</td>
 <td>Lactate increase with exercise and can differentiate moderate-intensity exercise and high-intensity exercise. 
 Ketone responds to different types of exercises. These levels ensure safety during exercise.</td>
 <td>Very limited ability to differentiate between the type of exercise, and mixed levels show a slow increase with exercise</td>
 </tr>
 <tr>
 <td>Accelerometers and heart-rate sensors coupled with lactate sensing</td>
 <td>Might have potential to inform CL on both exercise type (E.g., running, swimming or weights) and intensity (low, moderate, high or interval)</td>
 <td>Non-specificity to exercise with stress, illness, medications, dehydration, and all potential modulators</td>
 </tr>
 </tbody>
</table>

<ul>
 <li>
 Information from&nbsp;physiological signals&nbsp;like lactate, ketones, counterregulatory hormones, accelerometry, heart rate, galvaic skin response, skin temperature, and blood volume pulse could be used as potential adjunct for developing an algorithm about onset, offset and intensity of physical activity.</li>
 <li>
 Counterregulatory hormones&nbsp;can differentiate exercise intensity, however a lot of technical challenges were involved in measurement of them in real world.</li>
 <li>
 Other wearable&nbsp;sensors combining galvanic skin response, accelerometry, blood volume pulse, heart and skin temperature&nbsp;are able to classify the physical states and exercise type and could potentially differentiate exercise and physiological stress.</li>
</ul>

Additional signals

OTHER-DIABETES-TOPICS

DIABETES

<table border="1" cellpadding="1" cellspacing="1" style="width:100%;">
 <tbody>
 <tr>
 <td colspan="3" style="background-color: rgb(244, 242, 246);">
 Bi-hormonal CL systems 
 (Systems delivering both Insulin and glucagon)</td>
 </tr>
 <tr>
 <td style="background-color: rgb(244, 242, 246);">Strategies</td>
 <td style="background-color: rgb(244, 242, 246);">Advantages</td>
 <td style="background-color: rgb(244, 242, 246);">Limitations</td>
 </tr>
 <tr>
 <td>Glucagon helps in minimizing the impact of the delayed onset in insulin action by counteracting the persisting glucose-lowering effects of insulin</td>
 <td>
 <ul>
 <li>
 Bypass limitations of SC route</li>
 <li>
 Improved time-in-range</li>
 <li>
 Less hypoglycemia during excercise</li>
 </ul></td>
 <td>
 <ul>
 <li>
 Stability and cost</li>
 <li>
 Long-term safety of glucagon</li>
 <li>
 Increased complexity of the system</li>
 </ul></td>
 </tr>
 </tbody>
</table>

BI hormonal CL systems

<h2>Improved usability of existing strategies</h2>
An&nbsp;exercise button&nbsp;could be integrated into CL device activation which triggers several adaptive changes, such as:
<ul>
 <li>
 Automatic increase in glucose at a preset time</li>
 <li>
 Modifications in the algorithm so that it becomes less aggressive in minimizing rises in glucose levels and more aggressive in minimizing falls in glucose</li>
 <li>
 A function to preprogram future recurrent scheduling for exercise (date and time) which could automatically set temporary targets 90 minutes prior.</li>
</ul>

Improved usability


Access all the content and events you need to continue growing as a health professional.

Welcome To Campus Sanofi KSA

OUT-OF-TAXONOMY

To read the full content, activate your Sanofi Campus account. Please confirm your email address in the email you received.

If you didn't receive our first email at {email} to confirm your account you can request a new one below. If you don't see it, you may need to check your spam folder.

This information will only be used to validate your account and will not be distributed.

title

Before starting exploring, we can suggest you specific and relevant content

Title

This website is for healthcare professionals only

Welcome to BP Sanofi Campus

Create new password

To offer you a personalised experience, you must

Your profile is incomplete

The ADCT gives a measure of how controlled the eczema is. Answer these 6 simple questions with your patient to find the ADCT score. It will indicate proper course of action.

Atopic dermatitis, a type of eczema, may be affecting your Patient's life in more ways than you know.

Take the Atopic Dermatitis Control Test (ADCT)

Enjoy more exclusive content{newline}by <a>registering today</a>

Already have an account? <a>Sign in here</a>

Best practices on optimising patient care

Get a customised view of the topics that you're interested in, along with the ability to save content to watch or read at a later date.

Unlimited access to premier content, white papers, case studies, research papers, webinars, training, and up-to-date scientific medical resources.

Personalised content based on your areas of interest

Connect and stay up-to-date with peers in your area of speciality and topics of interest through free events and leadership forums.

Please sign in to continue and read the full article

Please sign up to continue reading the full article.

We respect your privacy and will not share your information with any 3rd parties.

Topical guides written specifically for patients

Unlimited access to the latest patient guide guides and resources. Share content with your patients with easy-to-use online tools.

Please complete your profile to read the content.

Your profile is not validated yet. Please verify your inbox.

Restricted Access

We can't find the page you're looking for

You are going to a website that is not operated by Sanofi. Sanofi has no control over the content or availability of linked sites or resources, and accepts no liability or responsibility for them or for any loss or damage that may arise from your use of them. Please ensure that you read the legal and privacy policy sections of any third-party site to which you link.

You are about to leave Sanofi Campus website.

You are now leaving this site to visit a partner website.

Thank you for visiting COPD Sanofi Campus.

This website is for healthcare professionals only.

Welcome to COPD Sanofi Campus.

Welcome to COPD Sanofi Campus

Welcome to CSU Sanofi Campus

Please refresh the page to access the content

Sorry, something went wrong

We're usually a treasure chest of knowledge, but we couldn't find what you're looking for.

We were unable to find what you're searching for

You are about to leave Campus.sanofi/uk.

Images from <a>iStockphoto.com</a>, Fotolia.de, <c>gettyimages.de</c>, <d>pexels.com</d> and <e>photocase.de</e> were used for our websites.

Thank you for registering. Before we get started, we need to confirm your email address to ensure that we have the correct information.

Please follow these steps to complete your registration:

Would you like to receive future text messages about Beyfortus updates?

Sanofi is here to help support your patients, their families, and caregivers. For more information regarding Beyfortus®, call <a.callPhoneNumberBeyfortus>1-855-BEYFORTUS (1-855-239-3678)</a.callPhoneNumberBeyfortus> or sign up below to receive the latest updates via email or text. All fields are required.

Would you like to learn more about Beyfortus® (nirsevimab-alip) 50 mg and 100 mg injection? Leave us your contact details, and a Sanofi representative will be in touch. All fields are required.

Would you also like to receive future messages and updates about Beyfortus?

Do you want to participate in the Beyfortus Reservation Program?

What information are you interested in learning more about? (Optional)

Are you enrolled in CENRIFKI REMS?

Request a visit from your local ALPROLIX representative to learn more. Call <a.callPhoneNumberAltuviiio>1-800-745-4447</a.callPhoneNumberAltuviiio>, Option 5, or complete the form below. The information you provide will be maintained in accordance with our <a.usPrivacyPolicy>Privacy Policy</a.usPrivacyPolicy>. All fields are required.

Request a visit from your local ALTUVIIIO representative to learn more. Call <a.callPhoneNumberAltuviiio>1-800-745-4447</a.callPhoneNumberAltuviiio>, Option 5, or complete the form below. The information you provide will be maintained in accordance with our <a.usPrivacyPolicy>Privacy Policy</a.usPrivacyPolicy>. All fields are required.

Request a visit from your local QFITLIA representative to learn more. Call <a.callPhoneNumberAltuviiio>1-800-745-4447</a.callPhoneNumberAltuviiio>, Option 5, or complete the form below. The information you provide will be maintained in accordance with our <a.usPrivacyPolicy>Privacy Policy</a.usPrivacyPolicy>. All fields are required.

Sign up to schedule an office visit with your ALPROLIX® Representative or receive updates about ALPROLIX. Please complete the form below. The information you provide will be maintained in accordance with our <a.usPrivacyPolicy>Privacy Policy</a.usPrivacyPolicy>. All fields are required.

Sign up to schedule an office visit with your local Sanofi representative and/or to receive updates about Qfitlia. Please complete the form below. The information you provide will be maintained in accordance with our <a.usPrivacyPolicy>Privacy Policy</a.usPrivacyPolicy>. All fields are required (unless otherwise specified).

All fields are required. (unless otherwise specified)

This site is intended for healthcare professionals only and contains information on Sanofi medicines, educational resources and more. Please click the appropriate button below. By entering this site, you are confirming that you are a healthcare professional. This site contains promotional information. Please note that some of the content on the website is only relevant for HCPs.

Welcome to Sanofi Campus

Welcome to ITP Sanofi Campus

This content is only available to registered users. Please sign in or register to view this content.

Please Sign In

Email verification

You're seeing a preview of the portal. Clear your cookies (by closing your browser window for example) to go back to public mode.

We've updated our privacy notice to better protect your data and enhance your experience. Please take a moment to review the changes by <privacyNewTab>clicking here</privacyNewTab>. Your privacy matters for us. Please click on continue to confirm you have read the new privacy notice.

Privacy Notice Update

Communication consent

My consents

Password

Confirm password

{resultsCount, plural, one {result} other {results}}

Please log in to access to the results

You need to sign-in to your account in order to access medical content.

Please Log In

To access the results, please register in under 1 minute

You are now leaving the Sanofi content section of our site and entering the external medical bibliographic search content section.

You are entering to the External Scientific Content Site

You are now leaving the external medical bibliographic search section of our site and entering the Sanofi content section.

Welcome To Campus Sanofi KSA

Scientific News

Additional signals

BI hormonal CL systems

Improved usability

Quick Links

Support for your patients

Payor