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benefits for patients


TZIELD (teplizumab) can give patients more symptom-free time in Stage 2 autoimmune T1D vs placebo, delaying a lifetime of symptom management and insulin therapy1-3

TZIELD is used to delay the onset of insulin-dependent T1D and can give people with pre-symptomatic T1D time to prepare for the future:

  • More time to learn about potential complications and what to look out for
  • More time to ensure they have the right care team by their side
  • More time to adapt to the lifestyle changes that come with daily T1D management


TZIELD could offer your patients additional years free from the social stigma and lifestyle disruptions that can come with managing autoimmune T1D symptoms:4-6

Counting carbs

Finger pricks

Insulin injections

Cost of supplies

Nights of interrupted sleep

Planning for travel

Driving with a fear of hypos

Future planning

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INDICATION: TZIELD is indicated to delay the onset of Stage 3 T1D in adult and paediatric patients 8 years of age and older with Stage 2 T1D.7

T1D, Type 1 diabetes.

  1. Sims EK, et al. Sci Transl Med. 2021; 13(583): eabc8980.
  2. Insel RA, et al. Diabetes Care. 2015; 38(10): 1964–1974.
  3. Lledó-Delgado A, et al. J Clin Invest. 2024; 134(18): e177492.
  4. Dybdal D, et al. Diabetologia. 2018; 61(4): 831–838.
  5. Ashraf MN and Cheng AYY. Diabetes Ther. 2024; 15(2): 311–316.
  6. Edelman S. J Fam Pract. 2023; 72(6 Suppl): S19–S24.
  7. TZIELD® (teplizumab) UK Summary of Product Characteristics. 2025.

MAT-XU-2500772 (v1.0) | November 2025