Rezurock▼ (Belumosudil) is intended for HCPs practising in Great Britain (England, Scotland and Wales) only.

TRANSPLANT

<h3>Advances in the biology of chronic GvHD</h3>

EBMT 2024: Advances in the biology of chronic GvHD

Length: 15mins
In this video, Professor Ernst Holler provides an overview with insights into how the pathophysiology and biology of chronic GvHD has evolved over the past decade. He discusses the sequence of events that lead to autoreactivity following transplantation, including the role of B-cells and antibody production. Holler also highlights the remaining gaps in our understanding, including risk factors and biomarker identification.

This is intended for HCPs practising in Great Britain (England, Scotland, Wales) only.

Download ROCKstar study summary. This is intended for HCPs practising in Great Britain (England, Scotland, Wales) only​.

Get in touch with the Transplant Team

Abbreviations

<h3>Frontline treatment of chronic GvHD</h3>

EBMT 2024: Frontline treatment of chronic GvHD

Length: 15mins
In this video, Dr Francesca Bonifazi discusses the current treatment paradigm for chronic GvHD. She explores frontline options and appropriate patient populations. Dr Bonifazi highlights the need for early intervention with cGvHD and how this may improve outcomes.

<h3>Treatment of steroid refactory chronic GvHD</h3>

EBMT 2024: Treatment of steroid refractory chronic GvHD

Length: 15mins
In this video, Professor Mohty provides an overview of SR-chronic GvHD, highlighting poor outcomes and the high mortality rate in this population. Mohty also explores the current treatment options for the individuals that have SR-chronic GvHD through theoretical patient cases.

<h3>QoL and cGvHD</h3>

EBMT 2024: QoL and chronic GvHD

Length: 15mins
Dr Kinsella highlights the varied nature of chronic GvHD symptoms in this video. She talks about how they can have a notable impact on the daily lives of patients. It also explores the treatment burden associated with chronic GvHD management, highlighting that individuals often require frequent hospital visits as well as multiple treatments to control their condition. Dr Kinsella discusses the side effects of some chronic GvHD treatments, (e.g. steroids), and how this can have a noteable impact on the overall quality of life of patients.

<h3>Roundtable: Exploring clinical cases</h3>

EBMT 2024: Roundtable: Exploring clinical cases

Length: 15mins
Following the presentation of an example of clinical cases by the co-chairs, the faculty engaged in a dynamic discussion that ascertained how they would approach the management of this patient.

<h3>Expanding the treatment paradigm with novel therapeutics</h3>

EBMT 2024: Expanding the cGvHD treatment paradigm with novel therapeutics

Length: 10mins
This video introduces novel therapies for chronic GvHD treatment, an overview of the MOAs, and an overiew of the key data from complete clinical trials.

In these roundtable discussions, patient case studies are discussed from countries (UK and Spain) to illustrate country-specific differences in the chronic GvHD treatment paradigm, including the use of Rezurock.
<h3>Management of chronic GvHD</h3>

EBMT 2024: Expert Exchange: Exploring the clinical practicalities of managing GvHD

Download ROCKstar study summary. This is intended for HCPs practising in Great Britain (England, Scotland, Wales) only​

<h3>The late effects of chronic GvHD: The challenge of long term management</h3>

EBMT 2024: The late effects of chronic GvHD: The challenge of long-term management

Length: 10 mins
Michelle Kenyon talks about the long-term complications associated with chronic GvHD in this video, as well as how these complications may vary in severity and impact patient quality of life.

<h3>Pulmonary chronic GvHD: The need for early identification and improved management</h3>

EBMT 2024: Pulmonary chronic GvHD: The need for early identification and improved management

Length: 15mins
In this video, Saskia Bos describes how pulmonary complications and high mortality rates in chronic GvHD emphasise the need for early identification and better management. She addresses the challenges in the diagnosis, the limitations of the NIH criteria, the need for treatment guidelines, the role of novel therapeutics, and more randomised trials.

The InTen Nurse Forum is a series of promotional meetings for GB HCPs only organised and funded by Sanofi. This Forum provides knowledge in the management of chronic Graft Versus Host Disease (GVHD), as well as an opportunity to hear from your peers on best practices.

For nurses and allied healthcare professionals with an interest in chronic GvHD

InTen Nurse Forum: What is chronic GvHD?

Length: 20:00
In this video you can learn from John the basics of chronic GvHD, how it impacts quality of life, its classification and measurement, and current treatment challenges.

John Murray is a nurse clinician in BMT at the Haematology and Transplant Unit of The Christie NHSFT where he first joined as the Transplant Coordinator and Apheresis nurse in 2001. Then he developed a new post of nurse clinician in BMT with a special interest in GvHD and late effects of transplant.
He has been Chair of the EBMT UK NAP group and also Chair of the EBMT scientific committee. He became President of EBMT NG in 2017, serving for 4 years and is currently a Past President. He gives regular presentations on issues related to transplantation with a special interest in GvHD. John is also Co-chair of the Equality Diversity and Inclusion committee of EBMT.

There will be more InTen Nurse Forum events in the coming months and we want to hear from you.&nbsp; 
Let us know what topics you are interested in by clicking below and fill out the form. Your voice will shape our future events.

Help us to shape our future events

InTen Nurse Forum - ACCEND Framework

Length: 09:00
In this video, Sara introduces the ACCEND (Aspirant Cancer Career and Education Development) programme for nurses and allied HCPs and its different components: Career pathway, core capabilities in practice and the educational framework.

Sara Main is a BMT and Cellular Therapy nurse at University Hospitals Southampton. Care of cancer patients has been the focus of almost all her nursing career. She is passionate about bone marrow transplant and committed to quality care for patients and families.
She is a committee member of EBMT UK NAP group and is dedicated to enhancing clinical, educational. and leadership skills to better support transplant and cellular therapy patient support at every step of their treatment pathway.
Sara emphasizes the critical role of quality in transplant and cell therapy nursing, advocating for patient safety and experience through education and governance activities.
Despite challenges, she believes in the profession's ability to lead change in treating these conditions and that it is an exciting time to be a BMT and Cellular Therapy nurse.

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