REZUROCK▼ (belumosudil) is intended for HCPs practising in the United Kingdom.

TRANSPLANT

<h2>Treating a cGVHD patient with steroid-related complications</h2>

Patient Case Study 9: Treatment of cGVHD with Steroid-related Complications

Dr Sandra Easdale&nbsp;and Dr Chloe Anthias from the Royal Marsden&nbsp;demonstrates how REZUROCK was used to treat a patient with chronic GVHD affecting the&nbsp;gastrointestinal tract&nbsp;and&nbsp;skin, while&nbsp;enabling steroid reduction&nbsp;to alleviate complications from prolonged corticosteroid therapy.

Explore 9 unique patient case studies from cGVHD centres across the UK.&nbsp;

Find more cGVHD patient cases studies&nbsp;

Get in touch with the Transplant Team

Abbreviations

<h2>Treating a patient with severe cGVHD</h2>

Patient Case Study 8: Treatment of Severe cGVHD

Dr Sandra Easdale&nbsp;and Dr Chloe Anthias from the Royal Marsden&nbsp;provided an overview of a patient who suffered with&nbsp;severe cGVHD&nbsp;affecting the&nbsp;lungs,&nbsp;skin&nbsp;and&nbsp;muscles.

Dr Sandra Easdale&nbsp;and Dr Chloe Anthias from the Royal Marsden&nbsp;presented two case studies of complex cGVHD patients at EBMT 2025 in Florence, Italy.

<h2>Dr Sandra Easdale: Treating a cGVHD patient with steroid-related complications</h2>

Patient Case Study Presentations - EBMT 2025

<h2>Dr Chloe Anthias: Treating a patient with NIH severe cGVHD&nbsp;</h2>

This case study was provided by&nbsp;Dr Maria Losa Maroto&nbsp;and Laura Hazlett&nbsp;from&nbsp;University Hospital Birmingham&nbsp;and provides an overview of a 41-year-old male patient who suffered with cGVHD in&nbsp;several organs.&nbsp;This patient experienced notable improvements in various organs and overall quality of life after starting REZUROCK treatment, following previous lines of therapy.&nbsp;

<div>
 Case Study 1: Treatment of cGVHD with several organs involved
</div>
<div>
 &nbsp;
</div>

This case study,&nbsp;provided by Dr. John Murray &amp; Dr. Sally Pickering, Advanced Practitioners in Haematology transplant at The Christie NHS Foundation Trust&nbsp;gives an overview of a patient who had initiated REZUROCK relatively soon after cGVHD diagnosis which affected multiple organs including the big muscles group, mouth, skin, liver, eyes and genitals.

Case Study 2: Treatment of Early cGVHD

This case study was provided by Dr. Mariam Amer &amp; Dr. Amy Creighton from Southampton University Hospital and presents a patient with significant cutaneous manifestations and organs involvement including Skin (NIH 3), Joints (NIH 3), Liver&nbsp;and Lungs.

Case Study 3: Treatment of Cutaneous cGVHD

This case study was provided by Dr. Serpil Vieira from Barts Health NHS, and demonstrates how REZUROCK was used successfully as a last-resort treatment for a patient with extensive sclerotic skin involvement and additional complications affecting the mouth, lungs, and GI tract.

Case Study 4: Treatment of Sclerotic Skin cGVHD

This case study was provided by&nbsp;Dr Alex Glover (Consultant Haematologist) &amp; Lynne Watson (Clinical Nurse Specialist) from Nottingham University Hospital NHS Trust.&nbsp;The case study examines a patient with severe chronic GVHD primarily affecting the lungs (NIH 3), with additional involvement of the eyes (NIH 2)&nbsp;and oral cavity (NIH 2)&nbsp;prior to starting on REZUROCK.

Case Study 5: Treatment of Severe cGVHD with NIH 3 Lung GVHD

This case study was&nbsp;provided by&nbsp;Dr Kirsty Sharplin (Consultant in Haematology) &amp; Francesca Toselli (Advanced Nurse Practitioner) from the Oxford University Hospitals NHS Foundation Trust.&nbsp;The case study highlights a patient with chronic GVHD primarily affecting the oral cavity (NIH 2), with additional liver involvement (NIH 2).

Case Study 6: Treatment of Oral cGVHD

This case study was provided by Dr Pakhshan Farshi, Consultant Haematologist at the Manchester Royal Infirmary and&nbsp;examines a patient with severe gastrointestinal cGVHD (NIH Grade 3-4), complicated by blood sugar instability and mobility issues prior to treatment with REZUROCK.

Case Study 7: Treatment of Gut cGVHD

This case study&nbsp;was provided by Dr Sandra Easdale &amp;&nbsp;Dr Chloe Anthias, Consultant Haematologists at The Royal Marsden Hospital in London&nbsp;and&nbsp;provides an overview of a patient who suffered with severe cGVHD affecting the lungs, skin and muscles.

Case Study 8:&nbsp;Treatment of NIH Severe cGVHD

This case study was provided by Dr Sandra Easdale &amp;&nbsp;Dr Chloe Anthias, Consultant Haematologists at The Royal Marsden Hospital&nbsp;in London and &nbsp;demonstrates how REZUROCK was used to treat a patient with chronic GVHD affecting the gastrointestinal tract&nbsp;and skin, while enabling steroid reduction to alleviate complications from prolonged corticosteroid therapy.

Case Study 9: Treatment of cGVHD with Steroid-related Complications

cGVHD Patient Case Studies

<a href="https://${link:{uuid:{d4dafd48-4837-4ef7-ab1b-76db53f754ab},repository:{dam},path:{/Portal/UK/Prescribing-links/dupixent-(dupilumab)-prescribing-information-ukdocument.pdf}}}" target="_blank">Dupixent (dupilumab) Prescribing Information UK</a>

<h2 style="color:#00A780;">HTA insights: Understanding Appraisals and Healthcare Value Assessments</h2>
Watch an&nbsp;insightful discussion on the Health Technology Assessment appraisal process and the roadmap to reimbursement.
Learn and watch how healthcare professionals can effectively participate in this process.

CHRONIC-OBSTRUCTIVE-PULMONARY-DISEASE-(COPD)

RESPIRATORY

HTA insights: Understanding Appraisals, Healthcare Value and Cost-effectiveness Assessments

MAT-XU-2501648 (v1.0) May 2025 |&nbsp;<a href="https://${link:{uuid:{d4dafd48-4837-4ef7-ab1b-76db53f754ab},repository:{dam},path:{/Portal/UK/Prescribing-links/dupixent-(dupilumab)-prescribing-information-ukdocument.pdf}}}" target="_blank">Dupixent (COPD) PI UK</a>

<h3 style="color:#00A780;">Navigating the Health Technology Assessment appraisal process</h3>
Our experts demystify the appraisal process, explain healthcare value assessment and cost-effectiveness for reimbursement. This overview provides valuable context for anyone interested in understanding how new treatments gain approval and reach patients in the healthcare system.

Dupixent (dupilumab) Prescribing Information UK

Prescribing information is available by clicking the links at the bottom of the page

<h2>Recording</h2>
Length: 22:21

TYPE-2-DIABETES

DIABETES

Paradigm 2024:
Anne Goodchild

Ketan Dhatariya&nbsp;&nbsp;

Get in touch with the Diabetes Team

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 <a href="${link:{uuid:{2a02177b-5764-4cb8-98b6-34b9445e0571},repository:{dam},path:{/Portal/UK/Prescribing-links/Toujeo-gb.pdf}}}">Prescribing Information&nbsp;GB</a> <a href="${link:{uuid:{1c698db8-7640-4fcd-b5c0-e84b58eb504a},repository:{dam},path:{/Portal/UK/Prescribing-links/toujeo-pi-ni.pdf}}}">Prescribing Information NI</a></td>
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 <a href="${link:{uuid:{97e86e26-07fe-49e8-b6f3-31758c4a1495},repository:{dam},path:{/Portal/UK/Prescribing-links/Lantus_GB.pdf}}}">Prescribing Information&nbsp;GB</a> <a href="${link:{uuid:{c13c2982-4e19-403a-91b1-4bad9b7bcc86},repository:{dam},path:{/Portal/UK/Prescribing-links/Lantus_NI.pdf}}}">Prescribing Information NI </a></td>
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Prescribing information is available by clicking the links at the bottom of the page
<h3>Diabetes Nurse Beth Kelly shares how to navigate hyperglycaemia after GLP-1s with insulin. She shares Toujeo data and a case study. </h3>

<h2>Recording</h2>
Length: 12:20

Recording of Diabetes UK 2024 - in collaboration with Diabetes Specialist Nurse Forum UK

Diabetes UK 2024:
Navigating Hyperglycaemia after GLP-1s with Insulin

Connecting the Dots: Benefits of pen connectivity for people living with diabetes

Sustainably scripting tomorrow with Sanofi&#39;s Planet Cares Program and Pen Recycling pilot

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 <a href="${link:{uuid:{97e86e26-07fe-49e8-b6f3-31758c4a1495},repository:{dam},path:{/Portal/UK/Prescribing-links/Lantus_GB.pdf}}}" target="_blank">Prescribing Information GB</a> <a href="${link:{uuid:{7ce33aa3-e36a-4e96-a8f7-31d6809acaf1},repository:{dam},path:{/Portal/UK/Prescribing-Information/Lantus-PI-NI.pdf}}}">Prescribing Information NI</a></td>
 </tr>
 </tbody>
</table>

<table border="1" cellpadding="1" cellspacing="1" style="width:500px;">
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 <a href="${link:{uuid:{2a02177b-5764-4cb8-98b6-34b9445e0571},repository:{dam},path:{/Portal/UK/Prescribing-links/Toujeo-gb.pdf}}}" target="_blank">Prescribing Information&nbsp;GB</a> <a href="${link:{uuid:{1c698db8-7640-4fcd-b5c0-e84b58eb504a},repository:{dam},path:{/Portal/UK/Prescribing-links/toujeo-pi-ni.pdf}}}" target="_blank">Prescribing Information NI</a></td>
 </tr>
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</table>

Recording of Diabetes UK 2024 - in collaboration with Diabetes Specialist Nurse Forum UK

<h2>Recording</h2>
Length: 15:49

Paradigm 2024:
Lesley Mills

<table border="1" cellpadding="1" cellspacing="1" style="width:500px;">
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 <a href="${link:{uuid:{8cd02cf2-bd72-495f-b720-698ef8d3f0da},repository:{dam},path:{/Portal/UK/Prescribing-links/Toujeo.pdf}}}" target="_blank">Prescribing Information UK</a> 
 &nbsp;</td>
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</table>

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 <a href="${link:{uuid:{acd7760d-f31d-4d7e-8b21-2cdf496d1cc2},repository:{dam},path:{/Portal/UK/Prescribing-links/Lantus_GB_NI.pdf}}}">Prescribing Information&nbsp;UK</a> 
 &nbsp;</td>
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<h2>Recording</h2>
Length: 17:19

Paradigm 2024:
Ketan Dhatariya 

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MAT-XU-2300297 (v3.0) - Date of preparation: October 2023

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Latest Education

Patient Case Study 9: Treatment of cGVHD with Steroid-related Complications

Patient Case Study 8: Treatment of Severe cGVHD

Patient Case Study Presentations - EBMT 2025

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Paradigm 2024: Anne Goodchild

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