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This website contains promotional content and is intended for Healthcare Professionals based in the United Kingdom only. Some content may only be relevant to HCPs practising in Great Britain (England, Scotland and Wales) according to product availability. This website is optimised for desktop use, and some features may perform differently on mobile devices.

Adverse event reporting can be found at the bottom of the page.

Lantus is indicated for the teatment of diabetes mellitus in adults, adolescents and children aged 2 years and above.1

Originally marketed in 2000, Lantus is available in 3 different presentations to suit varying patient needs:1

  • a 10ml vial
  • cartridge, compatible with the Allstar (full units) Pro and Juniorstar Pro (half-units) device
  • pre-filled pen
Lantus products

Start and switch guide

Download this summary guide on how to start or switch diabetes patients to Lantus or Toujeo (insulin glargine U300).

Long acting insulin overview

Download a table comparing the different long-acting insulin options available

Switching from different basal insulins to Lantus

Close metabolic monitoring is recommended during the switch and in the initial weeks thereafter, with potential dose adjustments and adjustments required to the patients’ treatment regime.1

From twice daily NPH insulin 

To reduce the risk of nocturnal and early morning hypoglycaemia, patients moving to a once daily regimen with Lantus should reduce their daily dose of basal insulin by 20-30% during the first weeks of treatment.1

From Toujeo (insulin glargine 300U/mL)

  • Lantus and Toujeo (insulin glargine 300 units/ml) are not bioequivalent and are not directly interchangeable.
  • To reduce the risk of hypoglycemia, patients should reduce their dose by approximately 20%.
  • During the first weeks the reduction should, at least partially, be compensated by an increase in mealtime insulin, after this period the regimen should be adjusted individually.

Starting patients on Lantus

Lantus should be administered once daily at any time but at the same time each day. The dose regimen (dose and timing) should be individually adjusted.1

For elderly patients, patients with renal or hepatic impairment insulin requirements may be diminished. 1

In patients with type 2 diabetes mellitus, Lantus can also be given together with orally active antidiabetic medicinal products.1

Patient Materials

Find resources and support for your patients on Lantus®. Help patients understand the basics of living and staying well with diabetes and how to have a positive start and experience with the medication prescribed to them.

Get in touch with the Diabetes Team

MAT-XU-2201444 (v7.0) Date of Preparation: March 2026  

Adverse events should be reported. Reporting forms and information can be found at www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store. Adverse events should also be reported to the Sanofi drug safety department on Tel: +44 (0) 800 0902 314. Alternatively, send via email to UK-drugsafety@sanofi.com