Article
Source: Campus Sanofi
May 19, 2025

Importance of assessing key disease domains in EOE

Author: Sanofi

Editorial Team

WHY IS IT IMPORTANT TO ASSESS MULTIPLE DISEASE DOMAINS IN EoE?

Outcomes from different disease domains may be discordant with one another¹⁴

Symptoms may persist and fibrotic changes may still occur despite histologic remission ^9,15,16
Symptoms may not be present despite endoscopic and histologic evidence of inflammation³
Subtle esophageal findings of EoE may not be recognized by the less-experienced endoscopist and routine endoscopic findings alone may not detect sections of reduced luminal diameter and microscopic inflammation, thereby requiring additional histologic assessments ^{9,14,15,17,18}
EoE specific QoL assessments may not correlate with mild forms of endoscopic features of EoE and basal layer hyperplasia, thus requiring confirmation from endoscopic and histologic findings ³

Comprehensive assessment using symptoms and QoL, histology, and endoscopy, enables an individualized, patient-centric approach to the management of EoE^7,9,11,15

References

WHY IS IT IMPORTANT TO ASSESS MULTIPLE DISEASE DOMAINS IN EoE?

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