- Article
- Source: Campus Sanofi
- Nov 25, 2025
Take a Closer Look at Heamophilia
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FACTOR VIII
Distribution is largely limited to the plasma and binds to von Willebrand factor4-

FACTOR IX
Has a widespread distribution in the extravascular space and binds to type IV collagen4,7,8

Based on a high Volume of distribution, THE MAJORITY OF FACTOR IX SPENDS ITS TIME IN THE EXTRAVASCULAR SPACE4


When assessing your patients with hemophilia B, consider a patient-centered approach that includes11,12:

Bleed rates

Joint bleed prevention

Adherence

Quality of life
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- American Thrombosis and Hemostasis Network. ATHN research report—ATHNdataset. Published June 30, 2019.
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- Gui T, et al. Blood. 2002;100(1):153–158.
- Björkman S, et al. Haemophilia. 2013;19(6):882–886.
- Dolan G. Blood Rev. 2018;32(1). doi:10.1111/hae.14046.
- Mann DM, et al. Haemophilia. 2021;27(3):332–339.
- McLaughlin JM, et al. Haemophilia. 2014;20(4):506–512.
- Srivastava A, et al. Haemophilia. 2020;26(suppl 6):1–158.
MAT-KW-2600168/V1/APR2026