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DUPIXENT® IS APPROVED ACROSS 7 INDICATIONS DRIVEN IN PART BY TYPE 2 INFLAMMATION WORLDWIDE1

 

ATOPIC DERMATITIS  
DUPIXENT is indicated for the treatment of moderate-to-severe atopic dermatitis in adults and adolescents 12 years and older who are candidates for systemic therapy. 
DUPIXENT is indicated for the treatment of severe atopic dermatitis in children 6 months to 11 years old who are candidates for systemic therapy.

ASTHMA 
DUPIXENT is indicated in adults and adolescents 12 years and older as add-on maintenance treatment for severe asthma with type 2 inflammation characterised by raised blood eosinophils and/or raised fraction of exhaled nitric oxide (FeNO), who are inadequately controlled with high dose inhaled corticosteroids (ICS) plus another medicinal product for maintenance treatment. 
DUPIXENT is indicated in children 6 to 11 years old as add-on maintenance treatment for severe asthma with type 2 inflammation characterised by raised blood eosinophils and/ or raised fraction of exhaled nitric oxide (FeNO), who are inadequately controlled with medium to high dose inhaled corticosteroids (ICS) plus another medicinal product for maintenance treatment.

PRURIGO NODULARIS (PN) 
DUPIXENT is indicated for the treatment of adults with moderate-to-severe prurigo nodularis who are candidates for systemic therapy.

 

CHRONIC RHINOSINUSITIS WITH NASAL POLYPS (CRSwNP) 
DUPIXENT is indicated as an add-on therapy with intranasal corticosteroids for the treatment of adults with severe CRSwNP for whom therapy with systemic corticosteroids and/or surgery do not provide adequate disease control.

EOSINOPHILIC ESOPHAGITIS (EoE) 
DUPIXENT is indicated for the treatment of eosinophilic esophagitis in adults, adolescents and children aged 1 year and older, weighing at least 15 kg, who are inadequately controlled by, are intolerant to, or who are not candidates for conventional medicinal therapy.

CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD) 
DUPIXENT is indicated in adults as add-on maintenance treatment for uncontrolled chronic obstructive pulmonary disease (COPD) characterised by raised blood eosinophils on a combination of an inhaled corticosteroid (ICS), a long-acting beta2-agonist (LABA), and a long-acting muscarinic antagonist (LAMA), or on a combination of a LABA and a LAMA if ICS is not appropriate.

CHRONIC SPONTANEOUS URTICARIA (CSU) 
DUPIXENT is indicated for the treatment of moderate to severe chronic spontaneous urticaria in adults, adolescents, and children (2 years and above) with inadequate response to H1 antihistamines and who are naive to anti-lgE therapy for CSU.

BULLOUS PEMPHIGOID (BP) 
DUPIXENT is indicated for the treatment of adult patients with bullous pemphigoid.

ALLERGIC FUNGAL RHINOSINUSITIS (AFRS) 
DUPIXENT is indicated for the treatment of adult and pediatric patients aged 6 years and older with allergic fungal rhinosinusitis who have a history of sino-nasal surgery.

aTriple inhaled therapy, or double inhaled therapy if ICS is inappropriate.

b>1,000,000 patients on therapy worldwide. Includes atopic dermatitis, asthma, chronic rhinosinusitis with nasal polyps, prurigo nodularis, eosinophilic esophagitis, chronic obstructive pulmonary disease, bullous pemphigoid, and chronic spontaneous urticaria.

H1, histamine receptor 1.

References: 

  1. DUPIXENT Summary of Product Characteristics, 2026.

  2. IQVIA Sanofi integrated DUPIXENT platform data through March 2026.

Dupixent API

MAT-SA-2600496/v1/September 2026