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Adverse event reporting can be found at the bottom of the page.

REZUROCK® 

(belumosudil) tablets

This is intended for HCPs practising in Great Britain (England, Scotland, Wales) only.

REZUROCK is recommended by NICE, within its marketing authorisation, for treating chronic graft-versus-host disease (chronic GVHD) in people 12 years and older after 2 or more systemic treatments.6

Profile

REZUROCK is indicated for the treatment of  patients aged 12 years old or older with chronic GVHD who have recieved at least two prior lines of systemic therapy.1

REZUROCK targets both the inflammatory and fibrotic processes of cGVHD through selective inhibition of the ROCK2 pathway.1-3

REZUROCK demonstrated efficacy in a broad range of patients with cGVHD.4

The safety profile of REZUROCK was evaluated across 2 multicenter clinical studies.4-5

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REZUROCK targets both the inflammatory and fibrotic processes of cGVHD through selective inhibition of the ROCK2 pathway.1-3

REZUROCK demonstrated efficacy in a broad range of patients with cGVHD.4

The safety profile of REZUROCK was evaluated across 2 multicenter clinical studies.4-5

Eligibility for REZUROCK

When any 2 prior lines of systemic therapy fail, consider REZUROCK.1

patient profiles image

 

Explore patient profiles eligible for REZUROCK after failure of any 2 prior lines of systemic therapy.

Dosing and Administration

A once-daily oral tablet for patients with cGVHD.1

  • Do not store REZUROCK above 25°C.
  • Each pale-yellow, oblong, 200-mg tablet is debossed with "KDM" on one side and “200” on the other side, with dimensions of 7.40x14.77mm.1 
  • REZUROCK should be dispensed to the patient in the original container only. Store in original container to protect from moisture. Replace cap securely each time after opening. Do not discard desiccant.1

Please refer to the full Summary of Product Characteristics before prescribing.

Patient Support 

Printer-Friendly Guide

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Suitable for those who prefer a physical copy or want to keep it handy.

Mobile-Friendly Guide

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Optimal for convenient access on mobile devices.

Mechanism of Action

How REZUROCK works

This video describes how REZUROCK targets both the inflammatory and fibrotic processes of cGvHD through selective inhibition of the ROCK2 pathway.1-3

Get in touch with the Transplant Team

MAT-XU-2305107 (v3.0) Date of Preparation: August 2024