- Article
- Source: Campus Sanofi
- 9 Oct 2025
4 min
IL4 and IL13 important role in Chronic Itch
Discover the science beyond histamine: This video reveals how chronic itch in atopic dermatitis is predominantly mediated through non-histaminergic pathways. Learn how IL-4 and IL-13, key drivers of type 2 inflammation, create a critical intersection between inflammatory cascades and neural itch signaling. Understand the clinical implications of targeting these dual cytokines to simultaneously address both inflammation and the persistent itch cycle that significantly impacts patient quality of life.
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