
GOLD 2026 Report: Key Updates for COPD Management
What’s New in the GOLD 2026 Report


What’s New in the GOLD 2026 Report

A simplified walkthrough of how 6‑month Confirmed Disability Progression (CDP) is measured in MS clinical trials. Dr. Barry Singer explains how EDSS changes are assessed, why sustained progression matters, and how this endpoint helps distinguish real, lasting disability worsening from temporary fluctuations.

Progression Independent of Relapse Activity (PIRA) represents the gradual, sustained worsening of disability that occurs even without relapses. In this video, Dr. Barry Singer explains how PIRA is defined, why it affects many patients across the MS spectrum, and how clinicians can better detect subtle changes that reflect true long-term progression.

Kaplan–Meier curves play a key role in visualizing how clinical events—such as confirmed disability progression—evolve over time in MS studies. In this video, Dr. Barry Singer provides a clear, simplified walkthrough of how these curves are constructed, how patient data contributes to each step, and what curve separation really tells us about treatment impact. This resource offers an accessible foundation for anyone looking to better understand KM interpretation in MS research.
Flu can lead to severe complications in high-risk populations, including older adults, pregnant women, and patients with chronic or immunocompromising conditions. This section provides key clinical insights, prevention strategies, and vaccination considerations to support healthcare professionals in protecting vulnerable patients and improving outcomes.
Podcast describing Umrah as mass gathering as well as the data related to the IMD modeling