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Man drinking hot drink peacefully outside
Man drinking hot drink peacefully outside

DUPIXENT®

(dupilumab) Severe Chronic Rhinosinusitis with Nasal Polyps

WELCOME BACK TO A LIFE WITH SUSTAINED CONTROL IN SEVERE CHRONIC RHINOSINUSITIS WITH NASAL POLYPS (CRSwNP)1

DUPIXENT sustained results across measures through to Week 52 vs placebo1

Give eligible patients results they can experience with DUPIXENT1

DUPIXENT is the first biologic that directly targets interleukin‑4 (IL-4) and IL-13 signalling to reduce type 2 inflammation in adults with severe CRSwNP1–3

TARGET

type 2 inflammation

TREAT

the symptoms of CRSwNP1

SUSTAINED  CONTROL

up to 52 weeks with less surgery or fewer steroids versus placebo4

Indication

DUPIXENT is indicated as an add‑on therapy with intranasal corticosteroids for the treatment of adults with severe CRSwNP for whom therapy with systemic corticosteroids and/or surgery does not provide adequate disease control.1

ABBREVIATIONS
CRSwNP, chronic rhinosinusitis with nasal polyps; IL-4/13, interleukin-4/13; NP, nasal polyps

REFERENCES

  1. DUPIXENT (dupilumab) Summary of Product Characteristics (UK).
  2. Gandhi NA, et al. Nat Rev Drug Discov. 2016;15(1):35‑50.
  3. Schleimer RP. Annu Rev Pathol. 2017;12:331‑57.
  4. Bachert C, et al. Lancet. 2019;394(10209):1638-50.

MAT-XU-2503881 (v1.0) | January 2026

Adverse events should be reported. Reporting forms and information can be found at www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store. Adverse events should also be reported to the Sanofi drug safety department on Tel: +44 (0) 800 0902 314. Alternatively, send via email to UK-drugsafety@sanofi.com