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Real-World Evidence Studies


RWE Not reviewed by SFDA 

CNR-MAT REGISTRY STUDY: A prospective study

Early treatment with first-line CABLIVI significantly reduced unfavorable outcomes vs historical controls* during the very acute phase of aTTP in this real-world setting.2

SPANISH: A retrospective study

Improved therapeutic outcomes were observed with CABLIVI used as first-line treatment vs historical controls* in patients with aTTP in a real-world setting.3

REACT-2020: An observational, retrospective cohort study 

First-line CABLIVI treatment vs non–first-line CABLIVI in a real-world cohort of patients with aTTP was associated with improved outcomes.4

AGGREGATED ANALYSIS: An aggregated analysis

Improved outcomes were seen in most cohorts receiving CABLIVI treatment vs non-CABLIVI treatment in an aggregated analysis of RCTs and RWE.4 

ITALIAN An observational, retrospective analysis 

Patients treated with CABLIVI showed better clinical outcomes, with tendentially shorter hospital stays and lower mortality rates.5 

→ Cablivi API

MAT-KW-2400342/V2/OCT2026