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Prescribing Information

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A new era in T1D

TZIELD is the first proactive intervention available to help address the immunological root cause of autoimmune T1D.1-4

About TZIELD

Clinical trial results

Discover the possibilities of the first and only approved disease-modifying therapy to delay disease progression.1,2,5

Efficacy data

Safety profile

Explore the safety profile of TZIELD, from a pool of adult and paediatric patients across five controlled clinical studies, four in Stage 3 T1D and one in
Stage 2 T1D.1

Safety data

Three distinct and detectable stages

Learn more about the three stages of autoimmune T1D.

Stages of T1D

Patient impact of T1D

Discover the potential physical and mental burden of autoimmune T1D.

Burden of T1D

Differentiating T1D from T2D

Explore how to differentiate T1D from Type 2 diabetes (T2D) to avoid misdiagnosis.

T1D vs T2D

Value of early detection

Discover the importance of detecting autoimmune T1D early for patients living with the disease.

Explore the benefits

Who to test

Discover the risk factors for autoimmune T1D.

Know the risk

How to test

Learn about the recommended tests for detecting autoimmune T1D.

Testing process

Monitoring presymptomatic T1D progression

Learn more about the next steps for patients who test positive for islet autoantibodies (AAbs).

Monitoring guidance

Resources

Discover downloadable resources and helpful links that can assist you and your patients through their T1D journey.

HCP resources

Peer-to-peer education

Access expert-led educational content on the latest understanding in autoimmune T1D.

BR1DGE

Explore the staging and progression of autoimmune T1D

Learn more about the three distinct and detectable stages of T1D.

About T1D

The importance of early detection

Proactive detection of autoimmune T1D facilitates access to treatment for patients with presymptomatic disease (Stage 2), with the potential to delay progression to symptomatic disease (Stage 3).1,6

Testing for T1D

Resources and support

A wide range of support materials for you and your patients to begin treatment with TZIELD.

Support Materials

Get in Touch with Us

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AAb, autoantibody; T1D, Type 1 diabetes; T2D, Type 2 diabetes.

  1. TZIELD® (teplizumab) UK Summary of Product Characteristics. 2025.
  2. Subramanian S, et al. BMJ. 2024; 384: e075681.
  3. Ramos EL, et al. N Engl J Med. 2023; 389(23): 2151–2161.
  4. Herold KC, et al. Nat Rev Immunol. 2024; 24(6): 435–451.
  5. Nagy G, et al. World J Diabetes. 2022; 13(10): 835–850.
  6. Sims EK, et al. Diabetes. 2022; 71: 610–623.

MAT-XU-2500755 (v1.0) | November 2025