Skip to main content
Altuviiio logo

ALTUVIIIO® Patient Experiences 


"ALTUVIIIO isn’t just hype, it’s done everything I wanted.”
 

Raising expectations

I definitely downplay the severity of my bleeds, and sometimes don’t even realize that I’m in as much pain as I actually am. I’ve heard many of my Blood Brothers say the same. I believe that many of us are used to what I’d call “old guidelines” or “expectations,” where we believe that we will always have pain and many bleeds a year, and we won’t be able to be active. But now, I know there are better treatment options that have great coverage at higher levels for a longer period of time.
 

Considering the switch

I had been following the development of ALTUVIIIO. Since I was switching from on-demand (PRN) to prophylaxis, I wanted the higher-for-longer Factor VIII levels that ALTUVIIIO provided, even compared with competitor EHLs.
 

Making the switch

My care team made things as simple as possible, and the Sanofi team also provided helpful support. I was on a PRN medication, but as a person with mild hemophilia, I had difficulty getting insurance to approve prophylaxis. After making the decision to switch and being prescribed ALTUVIIIO, my doctor had many calls with my insurance provider and the Sanofi team that ultimately got my factor approved. In the meantime, the 30-day trial gave me the chance to figure out whether ALTUVIIIO was the appropriate therapy for me.*
 

Life with ALTUVIIIO

I switched from on-demand to prophylaxis treatment for the first time in 2023, at the age of 40, when I started on ALTUVIIIO. I’ve found that infusing once a week isn’t all that difficult for me. Because I'm an outdoorsman, my joint health is especially important to me. For years, I’ve hiked in the mountains to go elk hunting, carrying a 40- to 60-pound pack 4 miles there and back. Since starting ALTUVIIIO, I have had zero breakthrough bleeds. I am thankful I am now treating prophylactically because it gives me extra protection from bleeds that I haven’t had for most of my life. 

This testimonial reflects one patient’s experience and has not been clinically evaluated. It is not intended to imply typical outcomes or substitute for clinical evidence. Tommy is a promotional speaker compensated by Sanofi.

EHL=extended half-life; PRN=as needed.

*Claims for free products dispensed through the Free Trial or Patient Assistance Programs shall not be submitted to any third-party payer, public or private (e.g. private insurance, Medicaid, Medicare, VA, DoD, TRICARE®, or similar federal or state programs) for reimbursement. All Programs not valid where prohibited by law. Sanofi reserves the right to modify or terminate the Programs at any time without notice. Program details provided upon registration.

Discover More Patient Experiences

Indication

ALTUVIIIO® [antihemophilic factor (recombinant), Fc-VWF-XTEN fusion protein-ehtl] is a von Willebrand Factor (VWF) independent recombinant DNA-derived, Factor VIII concentrate indicated for use in adults and children with Hemophilia A (congenital factor VIII deficiency) for:

  • Routine prophylaxis to reduce the frequency of bleeding episodes
  • On-demand treatment & control of bleeding episodes
  • Perioperative management of bleeding
Limitation of Use

ALTUVIIIO is not indicated for the treatment of von Willebrand disease.

Important Safety Information

Contraindications

ALTUVIIIO is contraindicated in patients who have had severe hypersensitivity reactions, including anaphylaxis, to the product or its excipients.

Warnings and Precautions
  • Allergic-type hypersensitivity reactions, including anaphylaxis, have occurred with ALTUVIIIO. Discontinue use of ALTUVIIIO if hypersensitivity reaction occurs and manage symptoms as appropriate.
  • Formation of neutralizing antibodies (inhibitors) to Factor VIII are possible following administration of ALTUVIIIO. Neutralizing antibodies were not reported in the clinical trials. Monitor all patients for the development of Factor VIII inhibitors by appropriate clinical observations and laboratory tests.
  • If assessment of plasma Factor VIII activity is needed, it is recommended to use a validated one-stage clotting assay. The ALTUVIIIO Factor VIII activity level is overestimated by the chromogenic assay and a specific ellagic acid-based aPTT reagent in one-stage clotting assay by approximately 2.5-fold. If these assays are used, divide the result by 2.5 to approximate the patient's ALTUVIIIO Factor VIII activity level.
Adverse Reactions

The most common adverse reactions (>10% of subjects) reported in clinical trials were headache and arthralgia.

Indication

Important Safety Information

© 2025 Sanofi. All rights reserved. ALTUVIIIO, MyALTUVIIIO, and Sanofi are registered trademarks of Sanofi or an affiliate. All other trademarks are the property of their respective owners, who have no affiliation or relationship with Sanofi. MAT-US-2508205-v1.0-11/2025 Last Updated: November 2025