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How to Differentiate Gaucher Disease Type 1

The Spectrum of Gaucher Disease Symptoms

The Risk of Factor VIII Inhibitors in Hemophilia A Treatment

Factor VIII (FVIII) replacement therapies have been a step forward for the prevention and treatment of bleeding episodes in patients with hemophilia A. One remaining challenge is the development of neutralizing antibodies, known as inhibitors, which interfere with patient response to a factor infusion or render it ineffective.

Hemophilia A in Women - Key Points to Discuss With Your Patients

Hemophilia A–a rare bleeding disorder–often goes undiagnosed in women because of the misconception that it only affects men, due to its X-linked recessive inheritance pattern. Although factor levels above 50% are usually considered within the normal range, emerging data suggest that some women and girls with levels between 50% and 60% may still have an increased risk of bleeding symptoms. Additionally, they may have sex-specific symptoms such as heavy menstrual bleeding and postpartum hemorrhage. This highlights the need for a more nuanced understanding of hemophilia A as it pertains to women.

RSV Transmission & Incubation Period

Respiratory syncytial virus (RSV) transmission is high, especially among young children and infants.¹ The incubation period for RSV varies, typically ranging from a few days to a week, before symptoms begin to manifest.^2,3

Understanding Viral Shedding in RSV

Viral shedding involves the release of infectious virions (virus particles) from an infected host into the environment, facilitating transmission to new hosts. Viral shedding is crucial for maintaining infections within populations.¹   In this article, we’ll be exploring viral shedding in the context of respiratory syncytial virus (RSV) infection.

Respiratory Syncytial Virus (RSV) Pathophysiology

Respiratory syncytial virus (RSV) is a common and highly contagious virus that primarily affects the respiratory tract, particularly in infants and young children.¹

Discussing Treatment Goals and Factor VIII Activity Assays With Hemophilia A Patients

Why is it important to accurately measure factor VIII activity levels when treating patients with hemophilia A? Because the results can help you tailor treatment plans and help inform personalized treatment goals. To aid in shared decision-making, it’s essential for patients to understand the significance of factor VIII activity level assay measurements. This knowledge can empower them to actively participate in their treatment plan, make informed decisions, and improve their day-to-day lives and overall well-being.