Vaccine hesitancy and concern over COVID-19 vaccine side effects have increased in the past year1-3*
As of February 2025, only 1 in 5 US adults had received an updated 2024-2025 COVID-19 vaccine2
In a 2024 survey, only 1 in 4 US adults said they would definitely get an updated COVID-19 vaccine1†
Among those not planning to get vaccinated, 56% cite side effects as a concern1†
Have you recommended a COVID-19 vaccine to your patients this season?
- Only 23% of patients reported having a healthcare provider recommend COVID-19 vaccination to them since July 2024.2‡
Your patients are at greater risk from COVID-19 if they are older, have comorbidities, or have not received a vaccine4,5
Patients who are at increased risk from COVID-194,5:
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OLDER ADULTS
- Patients aged ≥65 years make up 73% of all COVID-19 hospitalizations among adults§
- Risk of severe outcomes from COVID-19 increases substantially for patients aged 65 years and older
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PATIENTS WITH COMORBIDITIES
Risk of COVID-19 hospitalization is increased among adults with underlying medical conditions, including, but not limited to:
- Chronic kidney disease
- Diabetes
- Coronary artery disease
- Asthma
- History of stroke
- COPD
- Severe obesity
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UNVACCINATED PATIENTS
- Being unvaccinated or not being up to date on COVID-19 vaccinations increases the risk of severe COVID-19 outcomes
- The majority of adults hospitalized with COVID-19 had not received an updated COVID-19 vaccine since September 2022
- 3/4 of adults aged 65 and older who were hospitalized with COVID-19 had not received the recommended 2023-2024 COVID-19 vaccine
From September 2023 to October 2024, the COVID-19 hospitalization rate was ~2x higher than flu.6¶
Protection against COVID-19 may also mean protection from Long COVID7
Long COVID symptoms can be a significant burden to your patients after a COVID-19 infection:
- One study of 8 major healthcare systems found that persistent symptoms were present 1 year after initial infection in 18.3% of patients8#
- It is estimated that over 1 million Americans are out of the workforce at any given time due to Long COVID9
- A recent study found that patients who were hospitalized within 30 days after COVID-19 infection had a 29% higher risk of death 3 years later compared with people who did not get the virus10||
*Based on 2023 National Foundation for Infectious Diseases (NFID) Study compared to 2024 National Foundation for Infectious Diseases (NFID) Study data.1,3
†According to 2024 National Foundation for Infectious Diseases (NFID) Study; the survey was conducted on August 8-12, 2024 and included 1,160 complete responses—1,130 online and 30 by telephone—from US adults age 18 years and older.1
‡According to CDC data as of February 2025.2
§Based on COVID-NET data from October 2023 to September 2024.4
¶2023-2024 CDC Respiratory Virus Hospitalization Surveillance Network (RESP-NET) estimates of cumulative rates of flu and COVID-19 hospitalizations in the US.6
#Data from The Innovative Support for Patients with SARS-CoV-2 Infections Registry (INSPIRE).8
||Data from a study of ~135,000 people with SARS-CoV-2 infection and 5.2 million controls followed for 3 years.10
Could recommending a non-mRNA COVID-19 vaccine to your patients make a difference in vaccination rates?
References
1. Centers for Disease Control and Prevention. Vaccination uptake, intent, and confidence. April 2025. Accessed May 9, 2025. https://www.cdc.gov/respvaxview/dashboards/vaccination-behavioral-social-drivers.html 2. National Foundation for Infectious Diseases. 2024 National Survey: attitudes and behaviors about influenza, COVID-19, respiratory syncytial virus, and pneumococcal disease. September 2024. Accessed January 28, 2025. https://www.nfid.org/ resource/2024-national-survey-attitudes-and-behaviors-about-influenza-covid-19-respiratory-syncytial-virus-and-pneumococcal-disease/ 3. National Foundation for Infectious Diseases. 2023 attitudes about influenza, COVID-19, respiratory syncytial virus, and pneumococcal disease. September 2023. Accessed January 28, 2025. 4. Havers FP. COVID-19–Associated Hospitalizations—COVID-NET, February 2025 Update. Accessed May 9, 2025. https://www.cdc.gov/acip/downloads/slides-2025-04-15-16/03-Havers-COVID-508.pdf 5. Centers for Disease Control and Prevention. Underlying conditions and higher risk for severe COVID-19. February 2025. Accessed February 18, 2025. https://www.cdc.gov/covid/hcp/clinical-care/underlying-conditions.html 6. Centers for Disease Control and Prevention. Respiratory Virus Hospitalization Surveillance Network (RESP-NET). October 2024. Accessed May 15, 2025. https://www. cdc.gov/resp-net/dashboard/index.html 7. Centers for Disease Control and Prevention. Long COVID Basics. July 2025. Accessed August 11, 2025. https://www.cdc.gov/long-covid/about/index.html 8. Montoy JCC, Ford J, Yu H, et al. Prevalence of symptoms ≤12 months after acute illness, by COVID-19 status—United States, December 2020-March 2023. MMWR. 2023;72(32);859-865. 9. Centers for Disease Control and Prevention. Living with Long COVID. July 2025. Accessed August 11, 2025. https://www.cdc.gov/long-covid/living-with/index.html 10. Cai M, Xie Y, Topol EJ, Al-Aly Z. Three-year outcomes of post-acute sequelae of COVID-19. Nat Med. 2024 Jun;30(6):1564-1573. doi: 10.1038/s41591-024-02987-8.
