Chronische rhinosinusitis met neuspoliepen (CRSwNP)

Chronische Rhinosinusitis met Nasale Poliepen (CRSwNP): De verbinding tussen Type 2 Inflammatie en Reukverlies

Loss of Smell in CRSwNP

Loss of sense of smell is a common symptom of chronic rhinosinusitis with nasal polyps (CRSwNP), but its impact is often underestimated. Learn how olfactory dysfunction affects patient’s quality of life and explore the underlying mechanisms driving smell loss in CRSwNP.

DUPIREAL: Two-Year Turning Point with Dupilumab in CRSwNP

The results from the DUPIREAL real-world study reinforce the efficacy of dupilumab demonstrated in the SINUS-24 and SINUS-52 randomized clinical trials and are consistent with the approved SmPC.^1,2,3,4 DUPIREAL is the largest long-term real-world study (n=926) evaluating the effectiveness of dupilumab, including treatment response, disease control and remission, in severe uncontrolled CRSwNP over 2 years.^2,3

Real-World Evidence and Phase IV studies in CRSwNP

Patients with chronic rhinosinusitis with nasal polyps (CRSwNP) generally have a high symptom burden and poor health-related quality of life (QoL), often requiring recurring systemic corticosteroid use and repeated sinus surgery.

EVEREST study highlights

First ever direct Head-to-Head Comparison of Dupilumab vs Omalizumab in Patients with Severe CRSwNP and Coexisting Asthma.

Uncovering the Hidden Burden: Understanding Loss of Smell in CRSwNP

Navigating the Complexities of Smell Loss in Patients with CRSwNP.

Dupixent® CRSwNP

Algemene informatie chronische rhinosinusitis met neuspoliepen (CRSwNP)

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