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Patient Experiences - Daniel


“ALTUVIIIO’s treatment regimen and bleed protection has been good for me.”   
 

A treatment change during a life change 

I considered switching before, but I feared change. Plus, I was managing my hemophilia decently. My loved ones kept me on track. But that was before college. At school, there were changes in my environment that made frequent treatments harder. So that drew me to finally switch.     
 

It takes a team 

When I have a concern, I reach out to my care team immediately. So, during my switch to ALTUVIIIO, I knew they'd help me overcome my initial anxiety. I understood the benefits and potential risks, and I was able to switch more seamlessly than I was expecting.     
 

Living more freely 

ALTUVIIIO’s treatment regimen and bleed protection has been good for me. My factor levels stay higher for most of the week, and I have peace of mind about my level of protection. And with the once-weekly dosing regimen, I have the freedom to focus on the things I love.   
 

A look at the numbers 

I look at the PK curves in the context of PK curves on my prior treatment, and the value of ALTUVIIIO is clear to me. Between the time I started on it until now, the numbers have spoken for themselves. My Factor VIII levels stay higher for more days of the week. And the infusion process is incredibly similar to other medications I've used, so again, switching was not difficult.

 

Discussing a switch with patients 

I’d encourage other doctors to present all the information to patients in a way that’s easy to understand. Convey the potential advantages of switching. Discuss any restrictions and potential side effects. And be transparent, especially given how skeptical some patients can be. They may think there’s a “catch,” but doctors can show them that there could be benefits to considering a new treatment option.

This testimonial reflects one patient’s experience and has not been clinically evaluated. It is not intended to imply typical outcomes or substitute for clinical evidence. Daniel is a promotional speaker compensated by Sanofi. 

PK=pharmacokinetic.

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Indication

ALTUVIIIO® is indicated for use in adults and pediatric patients with hemophilia A (congenital factor VIII deficiency) for:

  • Routine prophylaxis to reduce the frequency of bleeding episodes
  • On-demand treatment and control of bleeding episodes
  • Perioperative management of bleeding
Limitation of Use

ALTUVIIIO is not indicated for the treatment of von Willebrand disease.

Important Safety Information

Contraindications

ALTUVIIIO is contraindicated in patients who have had severe hypersensitivity reactions, including anaphylaxis, to the product or its excipients.

Warnings and Precautions
  • Allergic-type hypersensitivity reactions, including anaphylaxis, have occurred with ALTUVIIIO. Discontinue use of ALTUVIIIO if hypersensitivity reaction occurs and manage symptoms as appropriate.
  • Formation of neutralizing antibodies (inhibitors) to Factor VIII has been reported following administration of ALTUVIIIO. Monitor all patients for the development of Factor VIII inhibitors by appropriate clinical observations and laboratory tests.
  • If assessment of plasma Factor VIII activity is needed, it is recommended to use a validated one-stage clotting assay. The ALTUVIIIO Factor VIII activity level is overestimated by the chromogenic assay and a specific ellagic acid-based aPTT reagent in one-stage clotting assay by approximately 2.5-fold. If these assays are used, divide the result by 2.5 to approximate the patient's ALTUVIIIO Factor VIII activity level.
Adverse Reactions

The most common adverse reactions (>10% of subjects) reported in clinical trials were headache and arthralgia.

Indication

Important Safety Information

© 2026 Sanofi. All rights reserved. All trademarks mentioned are the property of the Sanofi group. MAT-US-2508205-v3.0-08/2026 Last Updated: August 2026