Overview of cGvHD
GvHD leads to serious and potentially life-threatening complications from both inflammatory and fibrotic processes.⁴
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Startpaginachronic GRAFT-VERSUS-HOST DISEASE (cGVHD)
What is GvHD
GvHD occurs when immune cells transplanted from a donor (the graft) recognize the transplant recipient (the host) as foreign, thereby initiating an immune reaction that causes disease in the transplant recipient.1,2,3
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Guidelines cGvHD
Aim of cGvHD treatment and general considerations
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cGVHD criteria
cGvHD is characterized by a combination of tissue inflammation and fibrosis
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Justiz Vaillant AA, et al. Graft versus host disease. In: StatPearls. StatPearls Publishing; 2020. Updated September 19, 2020. Accessed August 20, 2020. https://www.ncbi.nlm.nih.gov/books/NBK538235;
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Henden AS, Hill GR. J Immunol. 2015;194(10):4604-4612. doi:10.4049/jimmunol.1500117;
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Ramachandran V, et al. Dermatol Clin. 2019;37(4):569-582. doi:10.1016/j.det.2019.05.014;