
Mechanism of Disease
Complex immune dysregulation can lead to autoimmunity and inflammation1-6
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Complex immune dysregulation can lead to autoimmunity and inflammation1-6

Patients reported significant quality of life (QoL) challenges related to their ITP1

Low platelet counts are one facet of ITP, but when we look at it from another angle, we see the multiple dimensions of ITP. ITP is a condition of complex immune dysregulation that reduces platelet counts—causing bleeding, bruising, fatigue, and other health-related quality-of-life (HRQoL) issues—while increasing inflammation and the risk of thromboembolic events (TEs).1-5

For ITP patients, several scales are available to measure and track fatigue and its impact on quality of life. These tools can help patients and healthcare providers gauge symptoms and adjust their ITP treatment accordingly.1-4
MAT-BE-2501247 v1.0-12-2025