What is GvHD

Overview of cGvHD

GvHD leads to serious and potentially life-threatening complications from both inflammatory and fibrotic processes.⁴

Guidelines cGvHD

Aim of cGvHD treatment and general considerations

cGVHD criteria

cGvHD is characterized by a combination of tissue inflammation and fibrosis

Effect of cGVHD

Immunological activation leads to ocular surface inflammation and lacrimal gland fibrosis in oGvHD.

Immunology mechanism

Antigen presentation is the process by which the body's cells present, via their HLA molecules, antigen proteins in the form of short peptides to the T-cell TCRs

Actors

Get to know these different actors who are involved in the mechanisms of alloreactivity.