Addressing Parental Concerns

Praise parents for their interest in seeking information and remind them that:

• RSV stands for respiratory syncytial virus. It’s a common, highly contagious virus that can lead to serious lung infections in babies. RSV season is typically from fall to spring, peaking in winter months^7,12,13
• As RSV is a common virus, many babies get it; more than half get it by age 1^12,14
• Typically a mild cold, it can quickly develop into a serious lung infection¹⁵
• RSV infection is a top cause of hospital stays in babies under 1 year. This is why we want to talk about protection for your baby^16,17*^†
    

*Based on leading primary diagnosis (RSV bronchiolitis, October 2015-December 2019, rank 1: 165,930 cases).^16 
†Estimated burden based on continuously collected surveillance data on patients hospitalized with laboratory-confirmed RSV.¹⁷
  

Acknowledge that questions about healthy babies are common; reinforce that you still recommend immunization.

• Yes, a serious RSV lung infection is also a risk for healthy babies. Historically, 3 out of 4 babies hospitalized due to RSV infection were healthy and born full term^18-20*
• Remind parents that a serious RSV lung infection is unpredictable—we can’t tell which babies will get seriously sick. That’s why helping to protect all eligible babies is important 
    

*These data are based on infants born April 2016 to February 2020 in the MarketScan Commercial (644,116), MarketScan Medicaid (1,025,286), and Optum Clinformatics (460,426) data sets; data from October 2014 to April 2015 among 1,176 RSV-hospitalized infants aged younger than 12 months; and data based on surveillance conducted in 2,149 hospitalized infants from October-March during the years 2000 through 2005.^18-20
  

Parents can equate past health with future protection, believing that their baby's health history translates into a lower risk of a serious RSV lung infection—even though clinical outcomes are unpredictable.²¹

Acknowledge that their baby’s age does influence risk, but does not eliminate it.

• Older infants entering their first RSV season can still get sick. They could wind up having to go to the doctor, urgent care, or the emergency room²²
• Of babies hospitalized due to RSV infection, approximately 4 in 10 were born in the spring or summer^23,24*
• The American Academy of Pediatrics (AAP) recommends an RSV preventive antibody, such as Beyfortus, for all eligible babies younger than 8 months^11†
    

*Dataset from 2016-2020 using 3 primary datasets: Merative MarketScan Commercial Claims and Encounters, MarketScan Multi-State Medicaid, and Optum’s de-identified Clinformatics Data Mart.^{24 

†}Recommended between October 1 and March 31. Timing of administration for RSV immunization may differ in certain areas.¹¹
  

Remind them that not all experiences will have the same outcomes.

• An older child not getting sick is not a guarantee that their baby sibling won’t get sick
• Your older child will be in contact with others. This can increase your baby’s exposure to RSV, which could lead to a serious lung infection²⁵
  • Of babies hospitalized due to a serious RSV lung infection, about half of their family members also tested positive for RSV, most likely a parent or older sibling
      

Some families believe good hygiene and cleaning can substitute for medical protection. Since RSV is easily transmitted, an extra layer of protection is recommended.^11,13

Acknowledge their effort and benefits of good hygiene. 

• RSV infection is highly contagious and can become serious. In addition, your baby will come into contact with many people and surfaces—at or away from home^13,25 
• Your older child being in contact with others gives more opportunities for exposure to your baby. RSV spreads easily through droplets, kisses, and contaminated surfaces, including baby toys. Keeping your baby away from others isn’t always enough to help keep them protected from a serious RSV lung infection^13,25 
• Remind parents of the unpredictability of RSV disease
    

Praise their knowledge of immunity. 

• A baby’s immune system may not yet be fully developed during their first RSV season. That’s why it’s important to help protect them when they’re most vulnerable^26,27
  • This applies whether they’re born during the RSV season or before it 
• Immunization is an effective way to help equip the immune system²⁸
• Beyfortus is a preventive antibody that can give your baby an extra layer of protection and it delivers antibodies right away⁶
    

Parents won’t embrace an option they know nothing about, even if it’s recommended. Information and reassurance are what they need. 

Ease their discomfort by letting them know you have a lot of information on, and experience with, Beyfortus.

• Beyfortus is a preventive antibody that helps immunize babies like yours from serious lung infections. It’s not a vaccine⁶
• Preventive antibodies have been trusted to help protect babies for over 25 years^8,9
• Beyfortus is designed to help protect babies during their first RSV season, when they need protection the most⁶
• Beyfortus was approved by the FDA in 2023. Since then, many doctors and nurses like me have trusted and chosen Beyfortus. In fact, more than 11 million babies have received it, and it’s the #1 prescribed RSV protection for babies like yours^5,6*^†
    

*IQVIA data through March 2026.^5 
†Supported by global estimated exposure based on calculation from sales volume data (September 1, 2023, through October 31, 2025). The number of children exposed is estimated based on the distribution of the recommended dose of Beyfortus administered, considering body weight, season of administration (1st or 2nd), and immunization plan.⁵
  

Ease their fears by sharing that Beyfortus isn’t new.

• Beyfortus was approved by the FDA in 2023. Since then, many doctors and nurses like me have trusted and recommend Beyfortus. In fact, more than 11 million babies have received it, and it’s the #1 prescribed RSV protection for babies like yours^5,6*^†
• Beyfortus is a preventive antibody that helps protect babies like yours from serious RSV lung infections. Preventive antibodies have been trusted to help protect babies for over 25 years^6,8,9
    

*IQVIA data through March 2026.^{5 

†}Supported by global estimated exposure based on calculation from sales volume data (September 1, 2023, through October 31, 2025). The number of children exposed is estimated based on the distribution of the recommended dose of Beyfortus administered, considering body weight, season of administration (1st or 2nd), and immunization plan.⁵
  

Acknowledge that immunization safety is a common concern

• Beyfortus has a well-documented safety profile. In clinical trials, safety was similar to that of placebo. This means that babies who received Beyfortus had about the same side effects as babies who received placebo^6,29,30*^†
• As with any immunization, Beyfortus can cause side effects⁶
• The long-term safety of Beyfortus is continuously being evaluated
• Serious allergic reactions have occurred. In clinical trials, common side effects included rash, pain, swelling, or a hard spot where babies got the shot. These are not all the possible side effects⁶

Remind parents of the unpredictability of a serious RSV lung infection and the risk of hospitalization.
  

*Adverse reactions were reported in 1.2% of infants who received Beyfortus; most (97%) adverse reactions were mild to moderate in severity and included rash (0.9%) and injection site reactions (0.3%) at an incidence higher than placebo.^6
†The Safety Population includes all infants who received the recommended dose of Beyfortus in Trials 04 and 03: Primary and Safety cohorts from Trial 04; infants who weighed less than 5 kg and who received the recommended dose of Beyfortus (single 50 mg IM dose) in Trial 03.⁶
  

Acknowledge that the long-term safety of immunizations is a concern you’ve heard before.

• The safety of Beyfortus has been tested and proven in multiple clinical trials, including in healthy babies like yours⁶*^†
• As with any immunization, Beyfortus can cause side effects⁶
• The long-term safety of Beyfortus is continuously being evaluated

Remind parents that preventive antibodies have been trusted to help protect babies for over 25 years.^6,8,9
  

*Adverse reactions were reported in 1.2% of infants who received Beyfortus; most (97%) adverse reactions were mild to moderate in severity and included rash (0.9%) and injection site reactions (0.3%) at an incidence higher than placebo.^6

†The Safety Population includes all infants who received the recommended dose of Beyfortus in Trials 04 and 03: Primary and Safety cohorts from Trial 04; infants who weighed less than 5 kg and who received the recommended dose of Beyfortus (single 50 mg IM dose) in Trial 03.⁶
  

Parents may have fears or safety concerns because media, including social media, can amplify fear-based concerns. This can happen even in the absence of accepted scientific evidence.³¹

Acknowledge that the safety of immunizations is a concern you’ve heard before.

• Beyfortus isn’t a vaccine; it’s a preventive antibody. That means it delivers antibodies right away to help protect your baby⁶
• Beyfortus doesn’t contain the virus and therefore cannot cause RSV infection^6,32
• Vaccines act like coaches—they teach the body how to protect itself. Preventive antibodies are like defenders— they help provide protection before infection³²
• The AAP recommends an RSV preventive antibody, such as Beyfortus, for all eligible babies younger than 8 months¹¹*
    

*Recommended between October 1 and March 31. Timing of administration for RSV immunization may differ in certain areas.¹¹
  

You’d see how how strained he was just trying to to breathe.

His lips started to turn blue.

We went straight to the emergency room.
 
He needed oxygen.
 
I just knew in my gut something was not right.
 
We felt helpless, scared.
 
I felt like it was my fault he was attached to all these different wires and tubes.
 
It was terrifying.
 
I remember actually begging one of the nurses to just do anything that she could to help.