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Beyfortus®▼(nirsevimab): effectiveness and public health impact in the real world

Gaucher disease in children

Gaucher disease is an autosomal recessive lysosomal storage disorder caused by pathogenic variants in the GBA1 gene, resulting in deficient activity of the enzyme acid β glucosidase.

Efficacy and safety of dupilumab in patients with PN with or without a history of atopic comorbidities

DUPIREAL: Two-Year Turning Point with Dupilumab in CRSwNP

The results from the DUPIREAL real-world study reinforce the efficacy of dupilumab demonstrated in the SINUS-24 and SINUS-52 randomized clinical trials and are consistent with the approved SmPC.^1,2,3,4 DUPIREAL is the largest long-term real-world study (n=926) evaluating the effectiveness of dupilumab, including treatment response, disease control and remission, in severe uncontrolled CRSwNP over 2 years.^2,3

Real-World Evidence and Phase IV studies in CRSwNP

Patients with chronic rhinosinusitis with nasal polyps (CRSwNP) generally have a high symptom burden and poor health-related quality of life (QoL), often requiring recurring systemic corticosteroid use and repeated sinus surgery.

Atopisch Eczeem bij kinderen

Verborgen ziektelast bij EoE eerder herkennen

Mechanism of Disease

Complex immune dysregulation can lead to autoimmunity and inflammation^1-6

Living with ITP

Patients reported significant quality of life (QoL) challenges related to their ITP¹